Varaico: Literature-Extracted Genetic Variants

RALGDS

219 papers

RefSeq Summary

Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular p...

Pfam Domains

RasGEF_Naa 115–227UCSCRasGEF N-terminal motif

RasGEFaa 389–596UCSCRasGEF domain

RAaa 798–885UCSCRas association (RalGDS/AF-6) domain

Gene Aliases

HGNC Name

ral guanine nucleotide dissociation stimulator

HGNC Alias Symbols

RGF; RalGEF; RGDS

Papers

RefSeq ID

Protein change

DNA change

1–12 of 164 variants

3 papers

NM_006266.4

p.A13P

c.37G>C

3 papers

NM_006266.4

p.R883Q

c.2648G>A

2 papers

NM_006266.4

p.Q3*

c.7C>T

2 papers

NM_006266.4

p.G15D

c.44G>A

2 papers

NM_006266.4

p.E100Q

c.298G>C

2 papers

NM_006266.4

p.K117R

c.350A>G

2 papers

NM_006266.4

p.R628Q

c.1883G>A

2 papers

NM_006266.4

p.A706V

c.2117C>T

2 papers

NM_006266.4

p.L858R

c.2573T>G

2 papers

NM_006266.4

p.L880L

c.2640C>G

1 paper

NM_006266.4

p.M1L

c.1A>T

1 paper

NM_006266.4

p.M1T

c.2T>C