Varaico: Literature-Extracted Genetic Variants

RALGDS

219 papers

RefSeq Summary

Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular p...

Pfam Domains

RasGEF_Naa 115–227UCSCRasGEF N-terminal motif

RasGEFaa 389–596UCSCRasGEF domain

RAaa 798–885UCSCRas association (RalGDS/AF-6) domain

Gene Aliases

HGNC Name

ral guanine nucleotide dissociation stimulator

HGNC Alias Symbols

RGF; RalGEF; RGDS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006266.4

p.R628Q

c.1883G>A

Surrounding Variants

1 paper

NM_006266.4

p.E637K

c.1909G>A

1 paper

NM_006266.4

p.S638Splc

c.1913+13C>G

1 paper

NM_006266.4

p.I605I

c.1815C>T

1 paper

NM_006266.4

p.E644G

c.1931A>G

1 paper

NM_006266.4

p.L645P

c.1934T>C

1 paper

NM_006266.4

p.P647S

c.1939C>T

1 paper

NM_006266.4

p.S669R

c.2005A>C

1 paper

NM_006266.4

p.K597_E598Splc

c.1791+5G>A

1 paper

NM_006266.4

p.S675S

c.2025C>T

2 papers

NM_006266.4

p.A706V

c.2117C>T

1 paper

NM_006266.4

p.I724L

c.2170A>C

1 paper

NM_006266.4

p.M581T

c.1742T>C