Varaico: Literature-Extracted Genetic Variants

RALGDS

219 papers

RefSeq Summary

Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular p...

Pfam Domains

RasGEF_Naa 115–227UCSCRasGEF N-terminal motif

RasGEFaa 389–596UCSCRasGEF domain

RAaa 798–885UCSCRas association (RalGDS/AF-6) domain

Gene Aliases

HGNC Name

ral guanine nucleotide dissociation stimulator

HGNC Alias Symbols

RGF; RalGEF; RGDS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006266.4

p.V462E

c.1385T>A

Surrounding Variants

1 paper

NM_006266.4

p.E464E

c.1392G>A

1 paper

NM_006266.4

p.R459W

c.1375A>T

1 paper

NM_006266.4

p.W466L

c.1397G>T

1 paper

NM_006266.4

p.S453R

c.1359C>G

1 paper

NM_006266.4

p.S453R

c.1359C>A

1 paper

NM_006266.4

p.S453R

c.1357A>C

1 paper

NM_006266.4

p.N451K

c.1353C>G

1 paper

NM_006266.4

p.N451K

c.1353C>A

1 paper

NM_006266.4

p.T446I

c.1337C>T

1 paper

NM_006266.4

p.S439I

c.1316G>T

1 paper

NM_006266.4

p.N438insFs

c.1313_1314insG

1 paper

NM_006266.4

p.S413P

c.1237T>C