Varaico: Literature-Extracted Genetic Variants

RALGDS

219 papers

RefSeq Summary

Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular p...

Pfam Domains

RasGEF_Naa 115–227UCSCRasGEF N-terminal motif

RasGEFaa 389–596UCSCRasGEF domain

RAaa 798–885UCSCRas association (RalGDS/AF-6) domain

Gene Aliases

HGNC Name

ral guanine nucleotide dissociation stimulator

HGNC Alias Symbols

RGF; RalGEF; RGDS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006266.4

p.V140V

c.420C>T

Surrounding Variants

1 paper

NM_006266.4

p.L137F

c.409C>T

1 paper

NM_006266.4

p.R148K

c.443G>A

1 paper

NM_006266.4

p.A131S

c.391G>T

1 paper

NM_006266.4

p.H127L

c.380A>T

1 paper

NM_006266.4

p.Q154L

c.461A>T

1 paper

NM_006266.4

p.Q155*

c.463C>T

1 paper

NM_006266.4

p.V125V

c.375G>A

1 paper

NM_006266.4

p.L124L

c.372G>A

1 paper

NM_006266.4

p.E122D

c.366G>C

1 paper

NM_006266.4

p.V116_A118del0

c.346_354del9

1 paper

NM_006266.4

p.K117N

c.351G>T

1 paper

NM_006266.4

p.K117N

c.351G>C