Varaico: Literature-Extracted Genetic Variants

RALGDS

219 papers

RefSeq Summary

Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular p...

Pfam Domains

RasGEF_Naa 115–227UCSCRasGEF N-terminal motif

RasGEFaa 389–596UCSCRasGEF domain

RAaa 798–885UCSCRas association (RalGDS/AF-6) domain

Gene Aliases

HGNC Name

ral guanine nucleotide dissociation stimulator

HGNC Alias Symbols

RGF; RalGEF; RGDS

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006266.4

p.Q3*

c.7C>T

Surrounding Variants

1 paper

NM_006266.4

p.V2V

c.6G>A

1 paper

NM_006266.4

p.M1_V2insFs

c.3_4insA

1 paper

NM_006266.4

p.M1I

c.3G>C

1 paper

NM_006266.4

p.M1I

c.3G>A

1 paper

NM_006266.4

p.M1T

c.2T>C

1 paper

NM_006266.4

p.M1L

c.1A>T

1 paper

NM_006266.4

p.M5I

c.15G>A

1 paper

NM_006266.4

p.E8Q

c.22G>C

1 paper

NM_006266.4

p.A13S

c.37G>T

3 papers

NM_006266.4

p.A13P

c.37G>C

1 paper

NM_006266.4

p.A13T

c.37G>A

1 paper

NM_006266.4

p.G14C

c.40G>T