Varaico: Literature-Extracted Genetic Variants

RASA3

98 papers

RefSeq Summary

This gene encodes a protein that binds inositol 1,3,4,5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. This protein functions as a negative regulator of the Ras signalling pathway. I...

Pfam Domains

C2aa 12–114UCSCC2 domain

C2aa 145–265UCSCC2 domain

RasGAPaa 351–423UCSCGTPase-activator protein for Ras-like GTPase

Gene Aliases

HGNC Name

RAS p21 protein activator 3

HGNC Alias Symbols

GAP1IP4BP; GAPIII

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007368.4

p.Y37insFs

c.109_110insTG

Surrounding Variants

1 paper

NM_007368.4

p.T39M

c.116C>T

1 paper

NM_007368.4

p.P30L

c.89C>T

1 paper

NM_007368.4

p.G29V

c.86G>T

2 papers

NM_007368.4

p.R49K

c.146G>A

1 paper

NM_007368.4

p.G19Splc

c.56-1782G>C