Varaico: Literature-Extracted Genetic Variants

RASGRF1

203 papers

RefSeq Summary

The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimul...

Pfam Domains

PHaa 23–129UCSCPH domain

RhoGEFaa 244–424UCSCRhoGEF domain

PHaa 458–584UCSCPH domain

RasGEF_Naa 647–760UCSCRasGEF N-terminal motif

Gene Aliases

HGNC Name

Ras protein specific guanine nucleotide releasing factor 1

HGNC Previous Symbol

GRF1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001145648.3

p.T561S

c.1681A>T

Surrounding Variants

1 paper

NM_001145648.3

p.P558L

c.1673C>T

1 paper

NM_001145648.3

p.A574V

c.1721C>T

1 paper

NM_001145648.3

p.E535K

c.1603G>A

2 papers

NM_001145648.3

p.E530G

c.1589A>G

1 paper

NM_001145648.3

p.E528K

c.1582G>A

1 paper

NM_001145648.3

p.D522N

c.1564G>A

1 paper

NM_001145648.3

p.L520F

c.1558C>T

1 paper

NM_001145648.3

p.P605P

c.1815G>A

1 paper

NM_001145648.3

p.G507E

c.1520G>A

1 paper

NM_001145648.3

p.G505G

c.1515C>G

1 paper

NM_001145648.3

p.I501M

c.1503C>G

1 paper

NM_001145648.3

p.L494insFs

c.1480_1481insG