Varaico: Literature-Extracted Genetic Variants

RASGRF2

88 papers

RefSeq Summary

RAS GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This gene encodes a calcium-regulated nucleotide exchange factor activating both RAS and RAS-related protein, RAC1,...

Pfam Domains

PHaa 23–133UCSCPH domain

RhoGEFaa 247–427UCSCRhoGEF domain

RasGEF_Naa 638–771UCSCRasGEF N-terminal motif

RasGEFaa 1005–1183UCSCRasGEF domain

Gene Aliases

HGNC Name

Ras protein specific guanine nucleotide releasing factor 2

HGNC Alias Symbols

GRF2; Ras-GRF2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006909.3

p.P62R

c.185C>G

Surrounding Variants

1 paper

NM_006909.3

p.A45T

c.133G>A

1 paper

NM_006909.3

p.P80S

c.238C>T

1 paper

NM_006909.3

p.A34ins1

c.101_102insATA

1 paper

NM_006909.3

p.G23S

c.67G>A