Ras protein specific guanine nucleotide releasing factor 2

GRF2

Ras-GRF2

Ras-specific guanine nucleotide-releasing factor 2

Ras guanine nucleotide exchange factor 2

RAS GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This gene encodes a calcium-regulated nucleotide exchange factor activating both RAS and RAS-related protein, RAC1, through the exchange of bound GDP for GTP, thereby, coordinating the signaling of distinct mitogen-activated protein kinase pathways. [provided by RefSeq, Oct 2011].

Varaico: Literature-Extracted Genetic Variants

RASGRF2

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols