Varaico: Literature-Extracted Genetic Variants

RASGRP1

113 papers

RefSeq Summary

This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleoti...

Pfam Domains

RasGEF_Naa 57–153UCSCRasGEF N-terminal motif

RasGEFaa 208–384UCSCRasGEF domain

C1_1aa 542–594UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Gene Aliases

HGNC Name

RAS guanyl releasing protein 1

HGNC Alias Symbol

CalDAG-GEFII

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005739.4

p.D371_Y372delFs

c.1111_1114del4

Surrounding Variants

1 paper

NM_005739.4

p.D371fs

c.1111_1112fs

1 paper

NM_005739.4

p.V380I

c.1138G>A

1 paper

NM_005739.4

p.L384L

c.1152G>A

1 paper

NM_005739.4

p.A385T

c.1153G>A

1 paper

NM_005739.4

p.L359V

c.1075C>G

1 paper

NM_005739.4

p.L355L

c.1063C>T

1 paper

NM_005739.4

p.K351N

c.1053G>T

1 paper

NM_005739.4

p.P401L

c.1202C>T

2 papers

NM_005739.4

p.R341Q

c.1022G>A

1 paper

NM_005739.4

p.S334S

c.1002C>T

1 paper

NM_005739.4

p.S332A

c.994T>G

1 paper

NM_005739.4

p.L413P

c.1238T>C