Varaico: Literature-Extracted Genetic Variants

RASGRP1

113 papers

RefSeq Summary

This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleoti...

Pfam Domains

RasGEF_Naa 57–153UCSCRasGEF N-terminal motif

RasGEFaa 208–384UCSCRasGEF domain

C1_1aa 542–594UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

Gene Aliases

HGNC Name

RAS guanyl releasing protein 1

HGNC Alias Symbol

CalDAG-GEFII

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005739.4

p.K322*

c.964A>T

Surrounding Variants

1 paper

NM_005739.4

p.N321S

c.962A>G

1 paper

NM_005739.4

p.K322_V323Splc

c.966+1G>T

1 paper

NM_005739.4

p.K322_V323Splc

c.966+5G>A

2 papers

NM_005739.4

p.S314L

c.941C>T

1 paper

NM_005739.4

p.S314*

c.941C>A

1 paper

NM_005739.4

p.T312A

c.934A>G

1 paper

NM_005739.4

p.S307L

c.920C>T

1 paper

NM_005739.4

p.H303N

c.907C>A

1 paper

NM_005739.4

p.L285del1

c.853_855delGAG

1 paper

NM_005739.4

p.R271*

c.811C>T

1 paper

NM_005739.4

p.S264R

c.792C>G

1 paper

NM_005739.4

p.S264R

c.792C>A