Varaico: Literature-Extracted Genetic Variants

RASSF1

115 papers

RefSeq Summary

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor su...

Pfam Domains

C1_1aa 52–108UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

RAaa 203–292UCSCRas association (RalGDS/AF-6) domain

Nore1-SARAHaa 299–338UCSCNovel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain

Gene Aliases

HGNC Name

Ras association domain family member 1

HGNC Alias Symbols

NORE2A; REH3P21; RDA32; 123F2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007182.5

p.C68S

c.202T>A

Surrounding Variants

7 papers

NM_007182.5

p.C65R

c.193T>C

1 paper

NM_007182.5

p.T63T

c.189G>A

1 paper

NM_007182.5

p.G74R

c.220G>C

1 paper

NM_007182.5

p.A60fs

c.178_179fs

1 paper

NM_007182.5

p.A60T

c.178G>A

4 papers

NM_007182.5

p.R77C

c.229C>T

1 paper

NM_007182.5

p.G58delFs

c.174delC

1 paper

NM_007182.5

p.P56P

c.168C>T

1 paper

NM_007182.5

p.G79_L80insFs

c.237_238insG

1 paper

NM_007182.5

p.R53C

c.157C>T

3 papers

NM_007182.5

p.H84Splc

c.250+2T>A

1 paper

NM_007182.5

p.G49G

c.147C>T