Varaico: Literature-Extracted Genetic Variants

RASSF1

115 papers

RefSeq Summary

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor su...

Pfam Domains

C1_1aa 52–108UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

RAaa 203–292UCSCRas association (RalGDS/AF-6) domain

Nore1-SARAHaa 299–338UCSCNovel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain

Gene Aliases

HGNC Name

Ras association domain family member 1

HGNC Alias Symbols

NORE2A; REH3P21; RDA32; 123F2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007182.5

p.P15L

c.44C>T

Surrounding Variants

1 paper

NM_007182.5

p.E12*

c.34G>T

4 papers

NM_007182.5

p.K21Q

c.61A>C

1 paper

NM_007182.5

p.E4D

c.12G>T

2 papers

NM_007182.5

p.E4D

c.12G>C

1 paper

NM_007182.5

p.E4E

c.12G>A

1 paper

NM_007182.5

p.R28H

c.83G>A

1 paper

NM_007182.5

p.I34I

c.102C>A

1 paper

NM_007182.5

p.C40Y

c.119G>A

1 paper

NM_007182.5

p.Q45*

c.133C>T

1 paper

NM_007182.5

p.V47F

c.139G>T

1 paper

NM_007182.5

p.G49G

c.147C>T

1 paper

NM_007182.5

p.R53C

c.157C>T