Varaico: Literature-Extracted Genetic Variants

RASSF5

76 papers

RefSeq Summary

This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubule...

Pfam Domains

C1_1aa 123–173UCSCPhorbol esters/diacylglycerol binding domain (C1 domain)

RAaa 274–364UCSCRas association (RalGDS/AF-6) domain

Nore1-SARAHaa 371–410UCSCNovel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain

Gene Aliases

HGNC Name

Ras association domain family member 5

HGNC Alias Symbols

Maxp1; NORE1; RAPL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_182663.4

p.R104W

c.310C>T

Surrounding Variants

1 paper

NM_182663.4

p.R101C

c.301C>T

1 paper

NM_182663.4

p.A97E

c.290C>A

1 paper

NM_182663.4

p.E118*

c.352G>T

1 paper

NM_182663.4

p.F125V

c.373T>G

1 paper

NM_182663.4

p.R81G

c.241C>G

1 paper

NM_182663.4

p.E127Q

c.379G>C

1 paper

NM_182663.4

p.E127D

c.381G>C

1 paper

NM_182663.4

p.E127D

c.381G>T

1 paper

NM_182663.4

p.G133D

c.398G>A

1 paper

NM_182663.4

p.C137R

c.409T>C

1 paper

NM_182663.4

p.A65T

c.193G>A

1 paper

NM_182663.4

p.E143Q

c.427G>C