Varaico: Literature-Extracted Genetic Variants

Gene:RBBP6
Variant:p.K1580E

RBBP6

216 papers

RefSeq Summary

The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylati...

Pfam Domains

DWNNaa 4–76UCSCDWNN domain
zf-CCHC_2aa 156–176UCSCZinc knuckle
U-boxaa 253–327UCSCU-box domain

Gene Aliases

HGNC Name

RB binding protein 6, ubiquitin ligase

HGNC Alias Symbols

P2P-R; PACT; SNAMA

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_006910.5
p.K1580E
c.4738A>G
Surrounding Variants
6 papers
NM_006910.5
p.R1569H
c.4706G>A
1 paper
NM_006910.5
p.E1595K
c.4783G>A
1 paper
NM_006910.5
p.V1561I
c.4681G>A
1 paper
NM_006910.5
p.N1555S
c.4664A>G
1 paper
NM_006910.5
p.R1540fs
c.4618_4619fs
1 paper
NM_006910.5
p.R1540delFs
c.4618_4619delAG
1 paper
NM_006910.5
p.P1536S
c.4606C>T
1 paper
NM_006910.5
p.D1528V
c.4583A>T
1 paper
NM_006910.5
p.D1528Y
c.4582G>T
1 paper
NM_006910.5
p.D1633V
c.4898A>T
1 paper
NM_006910.5
p.P1639P
c.4917A>G
1 paper
NM_006910.5
p.P1515L
c.4544C>T
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