Varaico: Literature-Extracted Genetic Variants

Gene:RBBP6
Variant:p.E1777D

RBBP6

216 papers

RefSeq Summary

The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylati...

Pfam Domains

DWNNaa 4–76UCSCDWNN domain
zf-CCHC_2aa 156–176UCSCZinc knuckle
U-boxaa 253–327UCSCU-box domain

Gene Aliases

HGNC Name

RB binding protein 6, ubiquitin ligase

HGNC Alias Symbols

P2P-R; PACT; SNAMA

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_006910.5
p.E1777D
c.5331G>C
Surrounding Variants
1 paper
NM_006910.5
p.E1777D
c.5331G>T
1 paper
NM_006910.5
p.K1776_E1777del2
c.5326_5330del6
1 paper
NM_006910.5
p.N1773fs
c.5317_5318fs
1 paper
NM_006910.5
p.H1763Q
c.5289C>A
1 paper
NM_006910.5
p.H1763Q
c.5289C>G
2 papers
NM_006910.5
p.H1763fs
c.5287_5288fs
1 paper
NM_006910.5
p.K1762_H1763delFs
c.5286_5287delAC
1 paper
NM_006910.5
p.E1754V
c.5261A>T
1 paper
NM_006910.5
p.H1741Q
c.5223T>A
1 paper
NM_006910.5
p.H1741Q
c.5223T>G
1 paper
NM_006910.5
p.K1732*
c.5194A>T
1 paper
NM_006910.5
p.K1733del1
c.5197_5198delAAG
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."