regulator of calcineurin 2

DSCR1L1

ZAKI-4

Down syndrome critical region gene 1-like 1

Calcipressin-2

Down syndrome candidate region 1-like 1

Myocyte-enriched calcineurin-interacting protein 2

Regulator of calcineurin 2

Thyroid hormone-responsive protein ZAKI-4

MCIP2

This gene encodes a member of the regulator of calcineurin (RCAN) protein family. These proteins play a role in many physiological processes by binding to the catalytic domain of calcineurin A, inhibiting calcineurin-mediated nuclear translocation of the transcription factor NFATC1. Expression of this gene in skin fibroblasts is upregulated by thyroid hormone, and the encoded protein may also play a role in endothelial cell function and angiogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011].

Varaico: Literature-Extracted Genetic Variants

RCAN2

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol