Varaico: Literature-Extracted Genetic Variants

Gene:REN
Variant:p.T375N

REN

929 papers

RefSeq Summary

This gene encodes renin, an aspartic protease that is secreted by the kidneys. Renin is a part of the renin-angiotensin-aldosterone system involved in regulation of blood pressure, and electrolyte bal...

Pfam Domains

A1_Propeptideaa 33–51UCSCA1 Propeptide
Aspaa 85–405UCSCEukaryotic aspartyl protease

Gene Aliases

HGNC Name

renin

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000537.4
p.T375N
c.1124C>A
Surrounding Variants
1 paper
NM_000537.4
p.P377H
c.1130C>A
1 paper
NM_000537.4
p.P373A
c.1117C>G
1 paper
NM_000537.4
p.P372A
c.1114C>G
1 paper
NM_000537.4
p.D370N
c.1108G>A
10 papers
NM_000537.4
p.L381P
c.1142T>C
1 paper
NM_000537.4
p.M369K
c.1106T>A
1 paper
NM_000537.4
p.A383T
c.1147G>A
1 paper
NM_000537.4
p.H367H
c.1101C>T
1 paper
NM_000537.4
p.I366I
c.1098C>T
1 paper
NM_000537.4
p.I366N
c.1097T>A
1 paper
NM_000537.4
p.T384I
c.1151C>T
1 paper
NM_000537.4
p.R387*
c.1159C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."