Varaico: Literature-Extracted Genetic Variants

Gene:REN
Variant:p.L24I

REN

929 papers

RefSeq Summary

This gene encodes renin, an aspartic protease that is secreted by the kidneys. Renin is a part of the renin-angiotensin-aldosterone system involved in regulation of blood pressure, and electrolyte bal...

Pfam Domains

A1_Propeptideaa 33–51UCSCA1 Propeptide
Aspaa 85–405UCSCEukaryotic aspartyl protease

Gene Aliases

HGNC Name

renin

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000537.4
p.L24I
c.70C>A
Surrounding Variants
1 paper
NM_000537.4
p.L24F
c.70C>T
1 paper
NM_000537.4
p.F22insFs
c.64_65insT
1 paper
NM_000537.4
p.G23R
c.67G>C
1 paper
NM_000537.4
p.T26_D27insG
c.76_80ins3
2 papers
NM_000537.4
p.T26I
c.77C>T
1 paper
NM_000537.4
p.D27H
c.79G>C
1 paper
NM_000537.4
p.T21A
c.61A>G
2 papers
NM_000537.4
p.C20*
c.60T>A
1 paper
NM_000537.4
p.D27G
c.80A>G
1 paper
NM_000537.4
p.D27E
c.81C>A
1 paper
NM_000537.4
p.C20insFs
c.58_59insG
11 papers
NM_000537.4
p.C20R
c.58T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."