Varaico: Literature-Extracted Genetic Variants

Gene:REST
Variant:p.P866L

REST

321 papers

RefSeq Summary

This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an onco...

Pfam Domains

zf-C2H2_RESTaa 157–186UCSCREST-like, C2H2-type zinc finger
zf-C2H2aa 304–326UCSCZinc finger, C2H2 type

Gene Aliases

HGNC Name

RE1 silencing transcription factor

HGNC Previous Symbol

DFNA27

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005612.5
p.P866L
c.2597C>T
Surrounding Variants
1 paper
NM_005612.5
p.L860H
c.2579T>A
1 paper
NM_005612.5
p.D879G
c.2636A>G
1 paper
NM_005612.5
p.L882I
c.2644T>A
1 paper
NM_005612.5
p.L882*
c.2645T>A
1 paper
NM_005612.5
p.L882*
c.2645T>G
4 papers
NM_005612.5
p.K890_E891delFs
c.2668_2671del4
1 paper
NM_005612.5
p.L842F
c.2526A>C
1 paper
NM_005612.5
p.L842F
c.2526A>T
3 papers
NM_005612.5
p.E891fs
c.2671_2672fs
1 paper
NM_005612.5
p.G841D
c.2522G>A
1 paper
NM_005612.5
p.P893fs
c.2677_2678fs
1 paper
NM_005612.5
p.I838M
c.2514T>G
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