Varaico: Literature-Extracted Genetic Variants

RET

5,388 papers

RefSeq Summary

This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related...

Pfam Domains

RET_CLD1aa 29–154UCSCRET Cadherin like domain 1

Cadherinaa 172–261UCSCCadherin domain

RET_CLD3aa 265–379UCSCRET Cadherin like domain 3

RET_CLD4aa 282–375UCSCRET Cadherin like domain 4

RET_CLD4aa 404–507UCSCRET Cadherin like domain 4

RET_CRDaa 518–620UCSCRET, Cysteine Rich Domain

Gene Aliases

HGNC Name

ret proto-oncogene

HGNC Previous Symbols

HSCR1; MEN2A; MTC1; MEN2B

Papers

RefSeq ID

Protein change

DNA change

1–12 of 3606 variants

1255 papers

NM_020975.6

p.M918T

c.2753T>C

736 papers

NM_020975.6

p.C634R

c.1900T>C

692 papers

NM_020975.6

p.V804M

c.2410G>A

420 papers

NM_020975.6

p.C634Y

c.1901G>A

400 papers

NM_020975.6

p.V804L

c.2410G>T

399 papers

NM_020975.6

p.V804L

c.2410G>C

356 papers

NM_020975.6

p.G691S

c.2071G>A

327 papers

NM_020975.6

p.C634W

c.1902C>G

296 papers

NM_020975.6

p.Y791F

c.2372A>T

228 papers

NM_020975.6

p.S891A

c.2671T>G

212 papers

NM_020975.6

p.L790F

c.2370G>C

212 papers

NM_020975.6

p.L790F

c.2370G>T