Varaico: Literature-Extracted Genetic Variants

RET

5,388 papers

RefSeq Summary

This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related...

Pfam Domains

RET_CLD1aa 29–154UCSCRET Cadherin like domain 1

Cadherinaa 172–261UCSCCadherin domain

RET_CLD3aa 265–379UCSCRET Cadherin like domain 3

RET_CLD4aa 282–375UCSCRET Cadherin like domain 4

RET_CLD4aa 404–507UCSCRET Cadherin like domain 4

RET_CRDaa 518–620UCSCRET, Cysteine Rich Domain

Gene Aliases

HGNC Name

ret proto-oncogene

HGNC Previous Symbols

HSCR1; MEN2A; MTC1; MEN2B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_020975.6

p.M1insFs

c.2_3insT

Surrounding Variants

1 paper

NM_020975.6

p.M1insFs

c.1_2insC

1 paper

NM_020975.6

p.M1ins1

c.1_2ins3

1 paper

NM_020975.6

p.M1insFs

c.1_2ins8

4 papers

NM_020975.6

p.M1L

c.1A>C

8 papers

NM_020975.6

p.M1V

c.1A>G

1 paper

NM_020975.6

p.M1L

c.1A>T

1 paper

NM_020975.6

p.M1delFs

c.2delT

2 papers

NM_020975.6

p.M1insFs

c.1dupA

1 paper

NM_020975.6

p.M1K

c.2T>A

2 papers

NM_020975.6

p.M1T

c.2T>C

1 paper

NM_020975.6

p.M1R

c.2T>G

1 paper

NM_020975.6

p.M1insFs

c.2_3insA