Varaico: Literature-Extracted Genetic Variants

RET

5,388 papers

RefSeq Summary

This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related...

Pfam Domains

RET_CLD1aa 29–154UCSCRET Cadherin like domain 1

Cadherinaa 172–261UCSCCadherin domain

RET_CLD3aa 265–379UCSCRET Cadherin like domain 3

RET_CLD4aa 282–375UCSCRET Cadherin like domain 4

RET_CLD4aa 404–507UCSCRET Cadherin like domain 4

RET_CRDaa 518–620UCSCRET, Cysteine Rich Domain

Gene Aliases

HGNC Name

ret proto-oncogene

HGNC Previous Symbols

HSCR1; MEN2A; MTC1; MEN2B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_020975.6

p.F31insFs

c.92_93insT

Surrounding Variants

1 paper

NM_020975.6

p.Y30*

c.90C>A

1 paper

NM_020975.6

p.Y30*

c.90C>G

2 papers

NM_020975.6

p.Y30F

c.89A>T

1 paper

NM_020975.6

p.F31L

c.91T>C

1 paper

NM_020975.6

p.F31V

c.91T>G

1 paper

NM_020975.6

p.F31Y

c.92T>A

1 paper

NM_020975.6

p.Y30delins

c.88delinsATGG

1 paper

NM_020975.6

p.Y30_F31insGGA

c.88_92ins9

1 paper

NM_020975.6

p.F31L

c.93C>A

1 paper

NM_020975.6

p.F31L

c.93C>G

1 paper

NM_020975.6

p.F31F

c.93C>T

1 paper

NM_020975.6

p.Y30delFs

c.88delT