Varaico: Literature-Extracted Genetic Variants

RET

5,388 papers

RefSeq Summary

This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related...

Pfam Domains

RET_CLD1aa 29–154UCSCRET Cadherin like domain 1

Cadherinaa 172–261UCSCCadherin domain

RET_CLD3aa 265–379UCSCRET Cadherin like domain 3

RET_CLD4aa 282–375UCSCRET Cadherin like domain 4

RET_CLD4aa 404–507UCSCRET Cadherin like domain 4

RET_CRDaa 518–620UCSCRET, Cysteine Rich Domain

Gene Aliases

HGNC Name

ret proto-oncogene

HGNC Previous Symbols

HSCR1; MEN2A; MTC1; MEN2B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_020975.6

p.G275insFs

c.825dupC

Surrounding Variants

1 paper

NM_020975.6

p.G275D

c.824G>A

1 paper

NM_020975.6

p.G275V

c.824G>T

1 paper

NM_020975.6

p.G275_V276insFs

c.825_826insA

2 papers

NM_020975.6

p.V276I

c.826G>A

2 papers

NM_020975.6

p.V276F

c.826G>T

1 paper

NM_020975.6

p.V276G

c.827T>G

1 paper

NM_020975.6

p.V276_D277insFs

c.828_829insA

1 paper

NM_020975.6

p.A274T

c.820G>A

1 paper

NM_020975.6

p.P273P

c.819C>T

1 paper

NM_020975.6

p.D277H

c.829G>C

1 paper

NM_020975.6

p.D277insFs

c.829_830insA

1 paper

NM_020975.6

p.D277Y

c.829G>T