Varaico: Literature-Extracted Genetic Variants

RET

5,388 papers

RefSeq Summary

This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related...

Pfam Domains

RET_CLD1aa 29–154UCSCRET Cadherin like domain 1

Cadherinaa 172–261UCSCCadherin domain

RET_CLD3aa 265–379UCSCRET Cadherin like domain 3

RET_CLD4aa 282–375UCSCRET Cadherin like domain 4

RET_CLD4aa 404–507UCSCRET Cadherin like domain 4

RET_CRDaa 518–620UCSCRET, Cysteine Rich Domain

Gene Aliases

HGNC Name

ret proto-oncogene

HGNC Previous Symbols

HSCR1; MEN2A; MTC1; MEN2B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_020975.6

p.V282_V283insCG

c.844_848ins6

Surrounding Variants

2 papers

NM_020975.6

p.V282L

c.844G>C

1 paper

NM_020975.6

p.V282insFs

c.845dupT

2 papers

NM_020975.6

p.V282L

c.844G>T

1 paper

NM_020975.6

p.V282delFs

c.845delT

1 paper

NM_020975.6

p.A281A

c.843C>T

1 paper

NM_020975.6

p.V282G

c.845T>G

1 paper

NM_020975.6

p.V282V

c.846G>A

1 paper

NM_020975.6

p.V282V

c.846G>C

2 papers

NM_020975.6

p.V283M

c.847G>A

2 papers

NM_020975.6

p.A281delFs

c.842delC

1 paper

NM_020975.6

p.V283G

c.848T>G

2 papers

NM_020975.6

p.E284delFs

c.850delG