Varaico: Literature-Extracted Genetic Variants

RET

5,388 papers

RefSeq Summary

This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related...

Pfam Domains

RET_CLD1aa 29–154UCSCRET Cadherin like domain 1

Cadherinaa 172–261UCSCCadherin domain

RET_CLD3aa 265–379UCSCRET Cadherin like domain 3

RET_CLD4aa 282–375UCSCRET Cadherin like domain 4

RET_CLD4aa 404–507UCSCRET Cadherin like domain 4

RET_CRDaa 518–620UCSCRET, Cysteine Rich Domain

Gene Aliases

HGNC Name

ret proto-oncogene

HGNC Previous Symbols

HSCR1; MEN2A; MTC1; MEN2B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_020975.6

p.G321delFs

c.961delG

Surrounding Variants

1 paper

NM_020975.6

p.P320P

c.960C>T

1 paper

NM_020975.6

p.P320_G321delFs

c.960_961delCG

24 papers

NM_020975.6

p.G321R

c.961G>A

24 papers

NM_020975.6

p.G321R

c.961G>C

1 paper

NM_020975.6

p.G321W

c.961G>T

1 paper

NM_020975.6

p.G321fs

c.961_962fs

1 paper

NM_020975.6

p.P320S

c.958C>T

1 paper

NM_020975.6

p.G321E

c.962G>A

1 paper

NM_020975.6

p.L319L

c.957C>A

1 paper

NM_020975.6

p.D322N

c.964G>A

1 paper

NM_020975.6

p.D322fs

c.964_965fs

1 paper

NM_020975.6

p.P320insFs

c.960dupC