Varaico: Literature-Extracted Genetic Variants

RET

5,388 papers

RefSeq Summary

This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related...

Pfam Domains

RET_CLD1aa 29–154UCSCRET Cadherin like domain 1

Cadherinaa 172–261UCSCCadherin domain

RET_CLD3aa 265–379UCSCRET Cadherin like domain 3

RET_CLD4aa 282–375UCSCRET Cadherin like domain 4

RET_CLD4aa 404–507UCSCRET Cadherin like domain 4

RET_CRDaa 518–620UCSCRET, Cysteine Rich Domain

Gene Aliases

HGNC Name

ret proto-oncogene

HGNC Previous Symbols

HSCR1; MEN2A; MTC1; MEN2B

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_020975.6

p.M1008delFs

c.3023delT

Surrounding Variants

1 paper

NM_020975.6

p.M1008V

c.3022A>G

1 paper

NM_020975.6

p.M1008T

c.3023T>C

3 papers

NM_020975.6

p.M1009V

c.3025A>G

3 papers

NM_020975.6

p.E1006D

c.3018G>C

3 papers

NM_020975.6

p.E1006D

c.3018G>T

4 papers

NM_020975.6

p.M1009T

c.3026T>C

2 papers

NM_020975.6

p.M1009I

c.3027G>A

2 papers

NM_020975.6

p.M1009I

c.3027G>C

2 papers

NM_020975.6

p.M1009I

c.3027G>T

2 papers

NM_020975.6

p.V1010I

c.3028G>A

1 paper

NM_020975.6

p.V1010L

c.3028G>C

1 paper

NM_020975.6

p.V1010insFs

c.3029_3030insT