Varaico: Literature-Extracted Genetic Variants

REV1

185 papers

RefSeq Summary

This gene encodes a protein with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role...

Pfam Domains

BRCTaa 44–118UCSCBRCA1 C Terminus (BRCT) domain

IMSaa 422–463UCSCimpB/mucB/samB family

Gene Aliases

HGNC Name

REV1 DNA directed polymerase

HGNC Previous Symbol

REV1L

Papers

RefSeq ID

Protein change

DNA change

1–12 of 169 variants

19 papers

NM_016316.4

p.F257S

c.770T>C

9 papers

NM_016316.4

p.N373S

c.1118A>G

8 papers

NM_016316.4

p.R704Q

c.2111G>A

7 papers

NM_016316.4

p.V138M

c.412G>A

4 papers

NM_016316.4

p.R434Q

c.1301G>A

4 papers

NM_016316.4

p.D570A

c.1709A>C

4 papers

NM_016316.4

p.E571A

c.1712A>C

3 papers

NM_016316.4

p.M392fs

c.1174_1175fs

2 papers

NM_016316.4

p.G209V

c.626G>T

2 papers

NM_016316.4

p.R219I

c.656G>T

2 papers

NM_016316.4

p.S328P

c.982T>C

2 papers

NM_016316.4

p.V446G

c.1337T>G