Varaico: Literature-Extracted Genetic Variants

RFC3

55 papers

RefSeq Summary

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC,...

Pfam Domains

DNA_pol3_delta2aa 18–188UCSCDNA polymerase III, delta subunit

RCF1-5-like_lidaa 194–235UCSCRCF1/5-like, AAA+ ATPase lid domain

RFC_Caa 251–347UCSCReplication factor C subunit 3, C-terminal domain

Gene Aliases

HGNC Name

replication factor C subunit 3

HGNC Alias Symbols

RFC38; MGC5276

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002915.4

p.I82N

c.245T>A

Surrounding Variants

1 paper

NM_002915.4

p.I82fs

c.244_245fs

1 paper

NM_002915.4

p.K81fs

c.241_242fs

3 papers

NM_002915.4

p.I82insFs

c.244dupA

2 papers

NM_002915.4

p.I82delFs

c.244delA

1 paper

NM_002915.4

p.K81_I82delFs

c.243_244delAA

1 paper

NM_002915.4

p.K79del1

c.235_236delAAA

1 paper

NM_002915.4

p.S78fs

c.232_233fs

1 paper

NM_002915.4

p.T76A

c.226A>G

1 paper

NM_002915.4

p.R105_E110del6

c.313_329del18

2 papers

NM_002915.4

p.R105*

c.313C>T

1 paper

NM_002915.4

p.E110Q

c.328G>C

1 paper

NM_002915.4

p.Q120H

c.360A>T