regulatory factor X3

regulatory factor X, 3 (influences HLA class II expression)

Transcription factor RFX3

Regulatory factor X 3

RFX1 transcription activation region      

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013].

Varaico: Literature-Extracted Genetic Variants

RFX3

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Name