Varaico: Literature-Extracted Genetic Variants

RHOBTB2

114 papers

RefSeq Summary

The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell divis...

Pfam Domains

Rasaa 16–209UCSCRas family

BTBaa 257–306UCSCBTB/POZ domain

BTBaa 380–472UCSCBTB/POZ domain

BTBaa 490–598UCSCBTB/POZ domain

Gene Aliases

HGNC Name

Rho related BTB domain containing 2

HGNC Alias Symbols

KIAA0717; DBC2

Papers

RefSeq ID

Protein change

DNA change

1–12 of 144 variants

10 papers

NM_001160036.2

p.R483H

c.1448G>A

9 papers

NM_001160036.2

p.R511Q

c.1532G>A

8 papers

NM_001160036.2

p.R507C

c.1519C>T

8 papers

NM_001160036.2

p.R511W

c.1531C>T

6 papers

NM_001160036.2

p.A474G

c.1421C>G

5 papers

NM_015178.3

p.Y284D

c.850T>G

5 papers

NM_001160036.2

p.N510D

c.1528A>G

4 papers

NM_001160036.2

p.R116C

c.346C>T

4 papers

NM_001160036.2

p.R154Q

c.461G>A

4 papers

NM_015178.3

p.D299N

c.895G>A

4 papers

NM_015178.3

p.R461H

c.1382G>A

4 papers

NM_001160036.2

p.R511G

c.1531C>G