Varaico: Literature-Extracted Genetic Variants

RHOBTB2

114 papers

RefSeq Summary

The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell divis...

Pfam Domains

Rasaa 16–209UCSCRas family

BTBaa 257–306UCSCBTB/POZ domain

BTBaa 380–472UCSCBTB/POZ domain

BTBaa 490–598UCSCBTB/POZ domain

Gene Aliases

HGNC Name

Rho related BTB domain containing 2

HGNC Alias Symbols

KIAA0717; DBC2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_001160036.2

p.R116C

c.346C>T

Surrounding Variants

1 paper

NM_001160036.2

p.D114E

c.342C>A

1 paper

NM_001160036.2

p.D114E

c.342C>G

3 papers

NM_001160036.2

p.D114H

c.340G>C

NM_015178.3

p.D92H

c.274G>C

1 paper

NM_001160037.2

p.G105E

c.314G>A

NM_001160036.2

p.G120E

c.359G>A

1 paper

NM_001160036.2

p.W105*

c.315G>A

2 papers

NM_001160036.2

p.W105*

c.314G>A

1 paper

NM_015178.3

p.R99Splc

c.296+30A>G

1 paper

NM_015178.3

p.S77N

c.230G>A

1 paper

NM_015178.3

p.D75_V76del2

c.223_227del6

1 paper

NM_015178.3

p.V73V

c.219A>T

1 paper

NM_015178.3

p.S69F

c.206C>T

1 paper

NM_015178.3

p.E64_V65Splc

c.193-8G>A