Varaico: Literature-Extracted Genetic Variants

RHOBTB2

114 papers

RefSeq Summary

The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell divis...

Pfam Domains

Rasaa 16–209UCSCRas family

BTBaa 257–306UCSCBTB/POZ domain

BTBaa 380–472UCSCBTB/POZ domain

BTBaa 490–598UCSCBTB/POZ domain

Gene Aliases

HGNC Name

Rho related BTB domain containing 2

HGNC Alias Symbols

KIAA0717; DBC2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001160036.2

p.R183M

c.548G>T

Surrounding Variants

1 paper

NM_001160036.2

p.R179*

c.535C>T

1 paper

NM_015178.3

p.R154K

c.461G>A

1 paper

NM_015178.3

p.A151_R156del0

c.452_466del15

1 paper

NM_015178.3

p.D148Y

c.442G>T

1 paper

NM_015178.3

p.Q141E

c.421C>G

4 papers

NM_001160036.2

p.R154Q

c.461G>A

3 papers

NM_001160036.2

p.R154L

c.461G>T

4 papers

NM_001160036.2

p.R154*

c.460C>T

NM_015178.3

p.R132*

c.394C>T

1 paper

NM_015178.3

p.M121I

c.363G>T

1 paper

NM_015178.3

p.H116Y

c.346C>T

1 paper

NM_015178.3

p.S114P

c.340T>C

1 paper

NM_015178.3

p.E167D

c.501A>T