Varaico: Literature-Extracted Genetic Variants

RHOBTB2

114 papers

RefSeq Summary

The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell divis...

Pfam Domains

Rasaa 16–209UCSCRas family

BTBaa 257–306UCSCBTB/POZ domain

BTBaa 380–472UCSCBTB/POZ domain

BTBaa 490–598UCSCBTB/POZ domain

Gene Aliases

HGNC Name

Rho related BTB domain containing 2

HGNC Alias Symbols

KIAA0717; DBC2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_001160036.2

p.W239C

c.717G>T

NM_015178.3

p.W217C

c.651G>T

Surrounding Variants

3 papers

NM_001160036.2

p.W239C

c.717G>C

NM_015178.3

p.W217C

c.651G>C

2 papers

NM_001160036.2

p.S241Y

c.722C>A

1 paper

NM_015178.3

p.R211H

c.632G>A

1 paper

NM_015178.3

p.P227S

c.679C>T

1 paper

NM_015178.3

p.P227L

c.680C>T

1 paper

NM_015178.3

p.A207A

c.621A>T

1 paper

NM_015178.3

p.R205Q

c.614G>A

1 paper

NM_001160036.2

p.P262L

c.785C>T

1 paper

NM_001160036.2

p.P263R

c.788C>G

1 paper

NM_015178.3

p.P241P

c.723G>A

1 paper

NM_015178.3

p.V244L

c.730G>C

1 paper

NM_015178.3

p.V244L

c.730G>T