Varaico: Literature-Extracted Genetic Variants

RHOBTB2

114 papers

RefSeq Summary

The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell divis...

Pfam Domains

Rasaa 16–209UCSCRas family

BTBaa 257–306UCSCBTB/POZ domain

BTBaa 380–472UCSCBTB/POZ domain

BTBaa 490–598UCSCBTB/POZ domain

Gene Aliases

HGNC Name

Rho related BTB domain containing 2

HGNC Alias Symbols

KIAA0717; DBC2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_015178.3

p.P263L

c.788C>T

Surrounding Variants

1 paper

NM_015178.3

p.E254_C255delFs

c.760_763del4

2 papers

NM_015178.3

p.R275W

c.823C>T

1 paper

NM_015178.3

p.V276M

c.826G>A

1 paper

NM_015178.3

p.S250C

c.749C>G

1 paper

NM_015178.3

p.P246L

c.737C>T

1 paper

NM_015178.3

p.V245A

c.734T>C

1 paper

NM_015178.3

p.H281Q

c.843C>A

1 paper

NM_015178.3

p.H281Q

c.843C>G

1 paper

NM_015178.3

p.K282R

c.845A>G

1 paper

NM_015178.3

p.V244L

c.730G>C

1 paper

NM_015178.3

p.V244L

c.730G>T

2 papers

NM_001160036.2

p.Y306N

c.916T>A