Varaico: Literature-Extracted Genetic Variants

RHOBTB2

114 papers

RefSeq Summary

The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell divis...

Pfam Domains

Rasaa 16–209UCSCRas family

BTBaa 257–306UCSCBTB/POZ domain

BTBaa 380–472UCSCBTB/POZ domain

BTBaa 490–598UCSCBTB/POZ domain

Gene Aliases

HGNC Name

Rho related BTB domain containing 2

HGNC Alias Symbols

KIAA0717; DBC2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001160036.2

p.S310S

c.930T>C

NM_015178.3

p.S288S

c.864T>C

Surrounding Variants

1 paper

NM_015178.3

p.S288insFs

c.863_864ins4

1 paper

NM_015178.3

p.T287_S288insFs

c.861_862insA

1 paper

NM_015178.3

p.K291E

c.871A>G

1 paper

NM_015178.3

p.S286insFs

c.858dupC

1 paper

NM_015178.3

p.F292_Y293delFs

c.875_878del4

2 papers

NM_001160036.2

p.Y306N

c.916T>A

7 papers

NM_015178.3

p.Y284D

c.850T>G

NM_001160036.2

p.Y306D

c.916T>G

1 paper

NM_015178.3

p.D294delFs

c.881delA

1 paper

NM_015178.3

p.K282R

c.845A>G

1 paper

NM_015178.3

p.H281Q

c.843C>A

1 paper

NM_015178.3

p.H281Q

c.843C>G

1 paper

NM_015178.3

p.F296delFs

c.886delT