Varaico: Literature-Extracted Genetic Variants

RHOBTB2

114 papers

RefSeq Summary

The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell divis...

Pfam Domains

Rasaa 16–209UCSCRas family

BTBaa 257–306UCSCBTB/POZ domain

BTBaa 380–472UCSCBTB/POZ domain

BTBaa 490–598UCSCBTB/POZ domain

Gene Aliases

HGNC Name

Rho related BTB domain containing 2

HGNC Alias Symbols

KIAA0717; DBC2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_015178.3

p.P316S

c.946C>T

Surrounding Variants

1 paper

NM_015178.3

p.G307C

c.919G>T

1 paper

NM_015178.3

p.E304delFs

c.910delG

1 paper

NM_015178.3

p.H333Y

c.997C>T

4 papers

NM_015178.3

p.D299N

c.895G>A

1 paper

NM_015178.3

p.R336Q

c.1007G>A

1 paper

NM_015178.3

p.F296delFs

c.886delT

1 paper

NM_015178.3

p.D294delFs

c.881delA

1 paper

NM_015178.3

p.F338_L339ins8

c.1014_1015ins24

1 paper

NM_015178.3

p.L340I

c.1018C>A

1 paper

NM_015178.3

p.F292_Y293delFs

c.875_878del4

1 paper

NM_015178.3

p.K291E

c.871A>G

2 papers

NM_001160036.2

p.S310S

c.930T>C

NM_015178.3

p.S288S

c.864T>C