Varaico: Literature-Extracted Genetic Variants

RHOBTB2

114 papers

RefSeq Summary

The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell divis...

Pfam Domains

Rasaa 16–209UCSCRas family

BTBaa 257–306UCSCBTB/POZ domain

BTBaa 380–472UCSCBTB/POZ domain

BTBaa 490–598UCSCBTB/POZ domain

Gene Aliases

HGNC Name

Rho related BTB domain containing 2

HGNC Alias Symbols

KIAA0717; DBC2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_015178.3

p.E349D

c.1047G>C

Surrounding Variants

3 papers

NM_015178.3

p.E349D

c.1047G>T

1 paper

NM_015178.3

p.D352N

c.1054G>A

1 paper

NM_015178.3

p.L340I

c.1018C>A

1 paper

NM_015178.3

p.F338_L339ins8

c.1014_1015ins24

1 paper

NM_015178.3

p.L362L

c.1086C>G

1 paper

NM_015178.3

p.R336Q

c.1007G>A

1 paper

NM_015178.3

p.H333Y

c.997C>T

2 papers

NM_015178.3

p.D368A

c.1103A>C

1 paper

NM_015178.3

p.P380L

c.1139C>T

1 paper

NM_015178.3

p.G383del1

c.1147_1149delGGT

1 paper

NM_015178.3

p.P316S

c.946C>T

1 paper

NM_015178.3

p.S387F

c.1160C>T