Varaico: Literature-Extracted Genetic Variants

RICTOR

501 papers

RefSeq Summary

RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[...

Pfam Domains

RICTOR_Naa 57–439UCSCRapamycin-insensitive companion of mTOR, N-term

RICTOR_Maa 637–740UCSCRapamycin-insensitive companion of mTOR, middle domain

RasGEF_N_2aa 746–853UCSCRapamycin-insensitive companion of mTOR RasGEF_N domain

Gene Aliases

HGNC Name

RPTOR independent companion of MTOR complex 2

HGNC Alias Symbols

MGC39830; AVO3; PIA; KIAA1999

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_152756.5

p.N1065S

c.3194A>G

Surrounding Variants

1 paper

NM_152756.5

p.E1066G

c.3197A>G

1 paper

NM_152756.5

p.D1063G

c.3188A>G

1 paper

NM_152756.5

p.P1070T

c.3208C>A

1 paper

NM_152756.5

p.T1057A

c.3169A>G

4 papers

NM_152756.5

p.D1074G

c.3221A>G

1 paper

NM_152756.5

p.S1055G

c.3163A>G

1 paper

NM_152756.5

p.R1051Q

c.3152G>A

1 paper

NM_152756.5

p.D1050G

c.3149A>G

1 paper

NM_152756.5

p.S1084L

c.3251C>T

1 paper

NM_152756.5

p.F1085L

c.3255C>A

1 paper

NM_152756.5

p.S1091N

c.3272G>A

1 paper

NM_152756.5

p.V1094L

c.3280G>T