Varaico: Literature-Extracted Genetic Variants

RIGI

518 papers

RefSeq Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration o...

Pfam Domains

CARD_2aa 1–93UCSCCaspase recruitment domain

DEADaa 41–217UCSCDEAD/DEAH box helicase

CARD_2aa 99–190UCSCCaspase recruitment domain

RIG-I_Caa 254–399UCSCRIG-I receptor C-terminal domain

Helicase_Caa 406–531UCSCHelicase conserved C-terminal domain

RIG-I_C-RDaa 603–720UCSCC-terminal domain of RIG-I

Gene Aliases

HGNC Name

RNA sensor RIG-I

HGNC Previous Symbol

DDX58

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

15 papers

NM_014314.4

p.D580E

c.1740T>G

Surrounding Variants

15 papers

NM_014314.4

p.D580E

c.1740T>A

2 papers

NM_014314.4

p.R575*

c.1723C>T

1 paper

NM_014314.4

p.Q588Q

c.1764G>A

1 paper

NM_014314.4

p.Q588delFs

c.1764delC

1 paper

NM_014314.4

p.F590C

c.1769T>G

1 paper

NM_014314.4

p.D569E

c.1707C>G

1 paper

NM_014314.4

p.D569E

c.1707C>A

1 paper

NM_014314.4

p.D569N

c.1705G>A

1 paper

NM_014314.4

p.D550A

c.1649A>C

1 paper

NM_014314.4

p.D550Y

c.1648G>T

7 papers

NM_014314.4

p.R546Q

c.1637G>A

1 paper

NM_014314.4

p.L538L

c.1612C>T