Varaico: Literature-Extracted Genetic Variants

RIGI

518 papers

RefSeq Summary

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration o...

Pfam Domains

CARD_2aa 1–93UCSCCaspase recruitment domain

DEADaa 41–217UCSCDEAD/DEAH box helicase

CARD_2aa 99–190UCSCCaspase recruitment domain

RIG-I_Caa 254–399UCSCRIG-I receptor C-terminal domain

Helicase_Caa 406–531UCSCHelicase conserved C-terminal domain

RIG-I_C-RDaa 603–720UCSCC-terminal domain of RIG-I

Gene Aliases

HGNC Name

RNA sensor RIG-I

HGNC Previous Symbol

DDX58

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014314.4

p.N354S

c.1061A>G

Surrounding Variants

1 paper

NM_014314.4

p.L351V

c.1051C>G

1 paper

NM_014314.4

p.P361L

c.1082C>T

4 papers

NM_014314.4

p.T347A

c.1039A>G

1 paper

NM_014314.4

p.S364A

c.1090T>G

1 paper

NM_014314.4

p.D372N

c.1114G>A

1 paper

NM_014314.4

p.D372A

c.1115A>C

4 papers

NM_014314.4

p.E373Q

c.1117G>C

24 papers

NM_014314.4

p.E373A

c.1118A>C

1 paper

NM_014314.4

p.E330K

c.988G>A

2 papers

NM_014314.4

p.Q380P

c.1139A>C

1 paper

NM_014314.4

p.Y383F

c.1148A>T

1 paper

NM_014314.4

p.N384D

c.1150A>G