Varaico: Literature-Extracted Genetic Variants

RIPK1

537 papers

RefSeq Summary

This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue d...

Pfam Domains

PK_Tyr_Ser-Thraa 18–285UCSCProtein tyrosine and serine/threonine kinase

Deathaa 584–669UCSCDeath domain

Gene Aliases

HGNC Name

receptor interacting serine/threonine kinase 1

HGNC Alias Symbols

RIP; RIP1; RIP-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001354930.2

p.Y387*

c.1161T>G

Surrounding Variants

1 paper

NM_001354930.2

p.S389insFs

c.1167dupC

1 paper

NM_001354930.2

p.S389delFs

c.1167delC

1 paper

NM_001354930.2

p.R390G

c.1168C>G

1 paper

NM_001354930.2

p.R390L

c.1169G>T

1 paper

NM_001354930.2

p.R393insFs

c.1178dupG

1 paper

NM_001354930.2

p.Q379K

c.1135C>A

3 papers

NM_001354930.2

p.K377R

c.1130A>G

1 paper

NM_001354930.2

p.Q398K

c.1192C>A

5 papers

NM_001354930.2

p.Q398*

c.1192C>T

1 paper

NM_001354930.2

p.K377E

c.1129A>G

1 paper

NM_001354930.2

p.Q398H

c.1194G>C

1 paper

NM_001354930.2

p.K377insFs

c.1129dupA