Varaico: Literature-Extracted Genetic Variants

RIPK1

537 papers

RefSeq Summary

This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue d...

Pfam Domains

PK_Tyr_Ser-Thraa 18–285UCSCProtein tyrosine and serine/threonine kinase

Deathaa 584–669UCSCDeath domain

Gene Aliases

HGNC Name

receptor interacting serine/threonine kinase 1

HGNC Alias Symbols

RIP; RIP1; RIP-1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001354930.2

p.K435Q

c.1303A>C

Surrounding Variants

1 paper

NM_001354930.2

p.G434G

c.1302A>G

1 paper

NM_001354930.2

p.E427K

c.1279G>A

7 papers

NM_001354930.2

p.Y426*

c.1278C>A

7 papers

NM_001354930.2

p.Y426*

c.1278C>G

5 papers

NM_001354930.2

p.H445Q

c.1335T>A

5 papers

NM_001354930.2

p.H445Q

c.1335T>G

1 paper

NM_001354930.2

p.Q422E

c.1264C>G

1 paper

NM_001354930.2

p.A448P

c.1342G>C

1 paper

NM_001354930.2

p.H450Y

c.1348C>T

1 paper

NM_001354930.2

p.P419S

c.1255C>T

1 paper

NM_001354930.2

p.V415insFs

c.1244dupT

1 paper

NM_001354930.2

p.Q458K

c.1372C>A