Varaico: Literature-Extracted Genetic Variants

RIPK2

166 papers

RefSeq Summary

This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CA...

Pfam Domains

PK_Tyr_Ser-Thraa 18–290UCSCProtein tyrosine and serine/threonine kinase

CARDaa 437–524UCSCCaspase recruitment domain

Gene Aliases

HGNC Name

receptor interacting serine/threonine kinase 2

HGNC Alias Symbols

RICK; RIP2; CARDIAK; CARD3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003821.6

p.K376E

c.1126A>G

Surrounding Variants

1 paper

NM_003821.6

p.D379A

c.1136A>C

1 paper

NM_003821.6

p.S396I

c.1187G>T

1 paper

NM_003821.6

p.Q402Q

c.1206A>G

1 paper

NM_003821.6

p.K410R

c.1229A>G

1 paper

NM_003821.6

p.A417V

c.1250C>T

1 paper

NM_003821.6

p.I418L

c.1252A>C

1 paper

NM_003821.6

p.I418L

c.1252A>T

1 paper

NM_003821.6

p.V448A

c.1343T>C

1 paper

NM_003821.6

p.N449D

c.1345A>G

1 paper

NM_003821.6

p.Q450K

c.1348C>A

1 paper

NM_003821.6

p.T452A

c.1354A>G

1 paper

NM_003821.6

p.T452K

c.1355C>A