Varaico: Literature-Extracted Genetic Variants

RIPK2

166 papers

RefSeq Summary

This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CA...

Pfam Domains

PK_Tyr_Ser-Thraa 18–290UCSCProtein tyrosine and serine/threonine kinase

CARDaa 437–524UCSCCaspase recruitment domain

Gene Aliases

HGNC Name

receptor interacting serine/threonine kinase 2

HGNC Alias Symbols

RICK; RIP2; CARDIAK; CARD3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003821.6

p.M470V

c.1408A>G

Surrounding Variants

1 paper

NM_003821.6

p.M470K

c.1409T>A

1 paper

NM_003821.6

p.K471*

c.1411A>T

1 paper

NM_003821.6

p.K471R

c.1412A>G

1 paper

NM_003821.6

p.E472A

c.1415A>C

1 paper

NM_003821.6

p.D473A

c.1418A>C

1 paper

NM_003821.6

p.D473V

c.1418A>T

1 paper

NM_003821.6

p.Y474F

c.1421A>T

1 paper

NM_003821.6

p.E475A

c.1424A>C

1 paper

NM_003821.6

p.D461A

c.1382A>C

1 paper

NM_003821.6

p.K480E

c.1438A>G

1 paper

NM_003821.6

p.P481A

c.1441C>G

1 paper

NM_003821.6

p.Q458K

c.1372C>A