Varaico: Literature-Extracted Genetic Variants

Gene:ROCK2
Variant:p.K64I

ROCK2

198 papers

RefSeq Summary

The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the...

Pfam Domains

Pkinaseaa 92–354UCSCProtein kinase domain
Rho_Bindingaa 978–1046UCSCRho Binding
PH_MRCKaa 1149–1257UCSCMRCK kinase PH domain

Gene Aliases

HGNC Name

Rho associated coiled-coil containing protein kinase 2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004850.5
p.K64I
c.191A>T
Surrounding Variants
1 paper
NM_004850.5
p.A61T
c.181G>A
1 paper
NM_004850.5
p.I78fs
c.232_233fs
1 paper
NM_004850.5
p.I78_V79delFs
c.233_237del5
1 paper
NM_004850.5
p.R83T
c.248G>C
3 papers
NM_004850.5
p.R83K
c.248G>A
1 paper
NM_004850.5
p.K96R
c.287A>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."