Varaico: Literature-Extracted Genetic Variants

ROR1

147 papers

RefSeq Summary

This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belong...

Pfam Domains

I-setaa 58–148UCSCImmunoglobulin I-set domain

Fzaa 170–289UCSCFz domain

Kringleaa 313–391UCSCKringle domain

PK_Tyr_Ser-Thraa 473–746UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

receptor tyrosine kinase like orphan receptor 1

HGNC Previous Symbol

NTRKR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005012.4

p.E562D

c.1686G>C

Surrounding Variants

1 paper

NM_005012.4

p.E562D

c.1686G>T

1 paper

NM_005012.4

p.D559N

c.1675G>A

1 paper

NM_005012.4

p.R567G

c.1699A>G

1 paper

NM_005012.4

p.M550L

c.1648A>C

1 paper

NM_005012.4

p.M550L

c.1648A>T

1 paper

NM_005012.4

p.S576R

c.1726A>C

1 paper

NM_005012.4

p.S576R

c.1728C>A

1 paper

NM_005012.4

p.S576R

c.1728C>G

1 paper

NM_005012.4

p.E579*

c.1735G>T

1 paper

NM_005012.4

p.D580fs

c.1738_1739fs

1 paper

NM_005012.4

p.D580_F592delFs

c.1740_1774del35

1 paper

NM_005012.4

p.V542I

c.1624G>A