Varaico: Literature-Extracted Genetic Variants

ROR1

147 papers

RefSeq Summary

This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belong...

Pfam Domains

I-setaa 58–148UCSCImmunoglobulin I-set domain

Fzaa 170–289UCSCFz domain

Kringleaa 313–391UCSCKringle domain

PK_Tyr_Ser-Thraa 473–746UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

receptor tyrosine kinase like orphan receptor 1

HGNC Previous Symbol

NTRKR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005012.4

p.D644N

c.1930G>A

Surrounding Variants

1 paper

NM_005012.4

p.A643T

c.1927G>A

1 paper

NM_005012.4

p.Y645F

c.1934A>T

1 paper

NM_005012.4

p.Y646F

c.1937A>T

1 paper

NM_005012.4

p.Y641F

c.1922A>T

1 paper

NM_005012.4

p.L636I

c.1906C>A

1 paper

NM_005012.4

p.L636fs

c.1906_1907fs

2 papers

NM_005012.4

p.R657C

c.1969C>T

1 paper

NM_005012.4

p.R657H

c.1970G>A

1 paper

NM_005012.4

p.P660H

c.1979C>A

1 paper

NM_005012.4

p.P660L

c.1979C>T

1 paper

NM_005012.4

p.P661S

c.1981C>T

2 papers

NM_005012.4

p.N620K

c.1860T>A