Varaico: Literature-Extracted Genetic Variants

RPS6KA1

150 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, incl...

Pfam Domains

Pkinaseaa 62–321UCSCProtein kinase domain

Pkinase_Caa 342–381UCSCProtein kinase C terminal domain

Pkinaseaa 418–675UCSCProtein kinase domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase A1

HGNC Alias Symbols

RSK1; HU-1; p90Rsk; MAPKAPK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_002953.4

p.S221A

c.661T>G

Surrounding Variants

1 paper

NM_002953.4

p.N235I

c.704A>T

1 paper

NM_002953.4

p.R236S

c.706C>A

1 paper

NM_002953.4

p.R236C

c.706C>T

2 papers

NM_002953.4

p.D205N

c.613G>A

1 paper

NM_002953.4

p.A277A

c.831G>A

1 paper

NM_002953.4

p.A295V

c.884C>T

1 paper

NM_002953.4

p.Y185*

c.555C>A

1 paper

NM_002953.4

p.Y185*

c.555C>G

1 paper

NM_002953.4

p.Y185F

c.554A>T

3 papers

NM_002953.4

p.A169A

c.507T>C

1 paper

NM_002953.4

p.P309L

c.926C>T

1 paper

NM_002953.4

p.R317Q

c.950G>A