Varaico: Literature-Extracted Genetic Variants

RPS6KA1

150 papers

RefSeq Summary

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, incl...

Pfam Domains

Pkinaseaa 62–321UCSCProtein kinase domain

Pkinase_Caa 342–381UCSCProtein kinase C terminal domain

Pkinaseaa 418–675UCSCProtein kinase domain

Gene Aliases

HGNC Name

ribosomal protein S6 kinase A1

HGNC Alias Symbols

RSK1; HU-1; p90Rsk; MAPKAPK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002953.4

p.R510Q

c.1529G>A

Surrounding Variants

1 paper

NM_002953.4

p.R510W

c.1528C>T

1 paper

NM_002953.4

p.V515D

c.1544T>A

1 paper

NM_002953.4

p.R503Q

c.1508G>A

1 paper

NM_002953.4

p.R503W

c.1507C>T

1 paper

NM_002953.4

p.L502M

c.1504C>A

1 paper

NM_002953.4

p.G520D

c.1559G>A

1 paper

NM_002953.4

p.K521R

c.1562A>G

1 paper

NM_002953.4

p.E524Q

c.1570G>C

1 paper

NM_002953.4

p.E524G

c.1571A>G

1 paper

NM_002953.4

p.G495E

c.1484G>A

1 paper

NM_002953.4

p.R493W

c.1477C>T

1 paper

NM_002953.4

p.G530R

c.1588G>A